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CTAK International

Corneal Tissue Addition for Keratoplasty (CTAK) is expanding internationally. Contact us to get started.

This innovative procedure offers an advanced solution for contouring keratoconic eyes and is designed to significantly improve sight for patients in need. Using CorneaGen’s Custom Tissue Inlays, CTAK provides patient-ready, gamma-irradiated sterile, non‑immunogenic donated corneal tissue inlays that are laser-cut and customized to patients’ specific severity and cone location.

 

Get Started with CTAK

CTAK International Brochure

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About CTAK

CTAK is the latest advancement in keratoconus treatment, focused on accuracy and precision for both patients and surgeons. This innovative procedure involves the use custom tissue inlays, designed to optimize corneal flattening, improve visual acuity, and add thickness to the cornea.

Using a Ziemer Neo Z8 Femtosecond Laser, CorneaGen processes tissue to the precise parameters for each patient. The tissue is sterilized, packaged and shipped with custom surgical plan options.

Advantages

CTAK is designed to improve visual outcomes, greater surgical precision, and faster recovery times.

  • Precision and accuracy of a Ziemer Z8 laser-cut custom tissue inlay
  • Biocompatible and fully customizable
  • Clinical study showed no rejection of tissue post-transplant
  • Custom surgical options detail inlay placement and sizing.
  • Topography flattening and visual acuity improvement
  • Gamma-irradiation adds rigidity to the inlay and stability for the surgeon

 

 

Recommended Patients

Moderate keratoconus: 50D-75D.

Patients with ectasia need more care and can schedule a consultation.

  • Moderate sized cones: ≤4.0mm in width
  • No cone which extends outside of the central 6mm optical zone (~3.0mm from the center of the pupil)
  • No scarring in the visual axis
Procedure Overview

White Papers

CTAK Long Term Outcomes

 

Corneal tissue addition keratoplasty: new intrastromal inlay procedure for keratoconus using femtosecond laser–shaped preserved corneal tissue.

Greenstein, Steven A. MD; Yu, Austin S. BA; Gelles, John D. OD; Eshraghi, Hamoon MD; Hersh, Peter S. MD.
Journal of Cataract & Refractive Surgery 49(7):p 740-746, July 2023. | DOI: 10.1097/j.jcrs.0000000000001187
Online Training

We’re excited to help you take the first step toward offering this innovative procedure by offering a short 15-20 minute online training course for surgeons interested in offering CTAK in their practice.

The online CTAK training will:

  • Introduce you to CTAK and its procedural requirements
  • Provide insights into patient selection and surgical planning
  • Offer step-by-step instructions to prepare you for hands-on practice

 

Visit CorneaGen.com/CTAKtraining and start today!

Educational Resources

To advance the transfer of knowledge within the cornea ecosystem, we offer world-class surgeon educational offerings.

CTAK Pearl: Patient Selection

Hear from CTAK co-creator, Peter Hersh, M.D. as he walks...

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CTAK: Surgical and Clinical Pearls Booth Talk at ASCRS 2025

CTAK creator, Peter Hersh, M.D., is joined by Elizabeth Davis,...

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CTAK Pearl: A Typical Case

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CTAK Pearl: Tear on the Channel

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CTAK Pearl: CTAK After Intacs Removal

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CTAK Pearl: Ectasia After LASIK

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CTAK Pearl: Procedure Location Logistics

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CTAK Pearl: Tighter Incisions

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CTAK – Surgical and Clinical Pearls

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VIEW ALL EDUCATIONAL RESOURCES

Get Started with CTAK Today

Keratoconus is a very frustrating disease with visual disability often requiring a corneal transplant when vision degrades to where glasses or contacts don’t work well. CTAK corneal tissue addition provides a great option for those patients with quick recovery, improved vision without the long recovery or risk of a corneal transplant. We’ve been very happy with the results.

David Hardten, M.D., F.A.C.S

Minnesota Eye Consultants

It’s pretty quick and easy! Overall I think CTAK is a fantastic procedure for patients with keratoconus that markedly improves uncorrected and best corrected vision without need for a more invasive PK or DALK

Elizabeth Davis, M.D., F.A.C.S

Minnesota Eye Consultants

Adverse Reaction Reporting

If you have had any complications occur in your recipients, we ask you please file a report with us so that we may comply with EBAA and FDA regulations.

More Information on Adverse Reaction Reporting

Regulatory Information

CorneaGen’s labs maintain the highest levels of quality through review by the U.S. Food and Drug Administration. For more information, please contact our Quality Assurance and Regulatory Affairs Department at (877) 682-8502.

View Regulatory Documents
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